[HTML][HTML] SARS-CoV-2 Omicron variant neutralization after mRNA-1273 booster vaccination

R Pajon, NA Doria-Rose, X Shen… - … England Journal of …, 2022 - Mass Medical Soc
R Pajon, NA Doria-Rose, X Shen, SD Schmidt, S O'Dell, C McDanal, W Feng, J Tong…
New England Journal of Medicine, 2022Mass Medical Soc
Omicron Neutralization and mRNA-1273 Boosters Neutralization of the omicron variant was
assessed in serum samples obtained from persons who had received an mRNA-1273
booster. After the standard two-dose vaccine regimen, these titers were approximately 35
times lower than those against the D614G variant. However, boosters increased omicron
neutralization by a factor of 20—to levels that correlate with clinical resistance to infection.
Omicron Neutralization and mRNA-1273 Boosters
Neutralization of the omicron variant was assessed in serum samples obtained from persons who had received an mRNA-1273 booster. After the standard two-dose vaccine regimen, these titers were approximately 35 times lower than those against the D614G variant. However, boosters increased omicron neutralization by a factor of 20 — to levels that correlate with clinical resistance to infection.
The New England Journal Of Medicine