Durability of immune response after COVID-19 booster vaccination and association with COVID-19 omicron infection
M Gilboa, G Regev-Yochay, M Mandelboim… - JAMA network …, 2022 - jamanetwork.com
Importance The BNT162b2 two-dose vaccine (BioNTech/Pfizer) has high effectiveness that
wanes within several months. The third dose is effective in mounting a significant immune
response, but its durability is unknown. Objective To compare antibody waning after second
and third doses and estimate the association of antibody kinetics with susceptibility to
infection with the Omicron variant of SARS-CoV-2. Design, Setting, and Participants In a
prospective longitudinal cohort study in a tertiary medical center in Israel, health care …
wanes within several months. The third dose is effective in mounting a significant immune
response, but its durability is unknown. Objective To compare antibody waning after second
and third doses and estimate the association of antibody kinetics with susceptibility to
infection with the Omicron variant of SARS-CoV-2. Design, Setting, and Participants In a
prospective longitudinal cohort study in a tertiary medical center in Israel, health care …