[HTML][HTML] An integrated genotyping approach for HLA and other complex genetic systems

WC Nelson, CW Pyo, D Vogan, R Wang, YS Pyon… - Human Immunology, 2015 - Elsevier
Clinical immunogenetics laboratories performing routine sequencing of human leukocyte
antigen (HLA) genes in support of hematopoietic cell transplantation are motivated to
upgrade to next-generation sequencing (NGS) technology by its potential for cost savings as
well as testing accuracy and flexibility. While NGS machines are available and simple to
operate, there are few systems available that provide comprehensive sample preparation
and data analysis workflows to complete the process. We report on the development and …