Increased fractional excretion of sulphate in stone formers
RC Puche, D Vaccaro, A Sanchez… - British journal of …, 1993 - Wiley Online Library
RC Puche, D Vaccaro, A Sanchez, A Gonzalez, HD Sarano
British journal of urology, 1993•Wiley Online LibraryThis study was performed to determine urinary sulphate excretion in patients with renal
stone disease. Stone formers showed a significantly higher fractional excretion of sulphate
than control subjects; 80% of stone formers had fractional excretions> 0.26. No significant
relationship was established between increased urinary sulphate excretion and any
identifiable metabolic disorder, or the recurrence rate of stone episodes. The increase in
fractional excretion of sulphate appears to be a more prevalent tubular defect among stone …
stone disease. Stone formers showed a significantly higher fractional excretion of sulphate
than control subjects; 80% of stone formers had fractional excretions> 0.26. No significant
relationship was established between increased urinary sulphate excretion and any
identifiable metabolic disorder, or the recurrence rate of stone episodes. The increase in
fractional excretion of sulphate appears to be a more prevalent tubular defect among stone …
Summary
This study was performed to determine urinary sulphate excretion in patients with renal stone disease. Stone formers showed a significantly higher fractional excretion of sulphate than control subjects; 80% of stone formers had fractional excretions > 0.26. No significant relationship was established between increased urinary sulphate excretion and any identifiable metabolic disorder, or the recurrence rate of stone episodes.
The increase in fractional excretion of sulphate appears to be a more prevalent tubular defect among stone formers than has hitherto been reported.
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