Relationship of dietary intake of sulphur amino-acids to urinary excretion of inorganic sulphate in man

ZI Sabry, SB Shadarevian, JW Cowan, JA Campbell - Nature, 1965 - nature.com
ZI Sabry, SB Shadarevian, JW Cowan, JA Campbell
Nature, 1965nature.com
As early as 1905, Wendt1 pointed out the importance of determining urinary sulphur in
studies of protein metabolism. The studies of Cathcart and Green2, Wilson3–5 and Basu et
al. 6 have demonstrated that most of the sulphur excreted as urinary sulphate in man results
from the oxidation of the sulphur amino-acids absorbed in the intestine and those from tissue
breakdown. It would be expected, therefore, that urinary sulphate would reflect, under
certain conditions, the amount of dietary sulphur amino-acids being absorbed, thus their …
Abstract
As early as 1905, Wendt1 pointed out the importance of determining urinary sulphur in studies of protein metabolism. The studies of Cathcart and Green2, Wilson3–5 and Basu et al.6 have demonstrated that most of the sulphur excreted as urinary sulphate in man results from the oxidation of the sulphur amino-acids absorbed in the intestine and those from tissue breakdown. It would be expected, therefore, that urinary sulphate would reflect, under certain conditions, the amount of dietary sulphur amino-acids being absorbed, thus their ‘biological availability’ from various foods. The present experiments were undertaken to investigate the relation between the sulphur amino-acids in the diet and the excretion of urinary inorganic sulphate in man.
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