Polyunsaturated fatty acid synthesis: what will they think of next?
JG Wallis, JL Watts - Trends in biochemical sciences, 2002 - cell.com
JG Wallis, JL Watts
Trends in biochemical sciences, 2002•cell.comPolyunsaturated fatty acids have crucial roles in membrane biology and signaling processes
in most living organisms. However, it is only recently that molecular genetic approaches
have allowed detailed studies of the enzymes involved in their synthesis. New evidence has
revealed a range of pathways in different organisms. These include a complex sequence for
synthesis of docosahexaenoic acid (22: 6) in mammals and a polyketide synthase pathway
in marine microbes.
in most living organisms. However, it is only recently that molecular genetic approaches
have allowed detailed studies of the enzymes involved in their synthesis. New evidence has
revealed a range of pathways in different organisms. These include a complex sequence for
synthesis of docosahexaenoic acid (22: 6) in mammals and a polyketide synthase pathway
in marine microbes.
Abstract
Polyunsaturated fatty acids have crucial roles in membrane biology and signaling processes in most living organisms. However, it is only recently that molecular genetic approaches have allowed detailed studies of the enzymes involved in their synthesis. New evidence has revealed a range of pathways in different organisms. These include a complex sequence for synthesis of docosahexaenoic acid (22:6) in mammals and a polyketide synthase pathway in marine microbes.
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