OBJECTIVE. The absence of cerebral autoregulation in preterm infants has been associated
with adverse outcome, but its bedside assessment in the immature brain is problematic. We
used spatially resolved spectroscopy to continuously measure cerebral oxygen saturation
(expressed as a tissue-oxygenation index) and used the correlation of tissue-oxygenation
index with spontaneous fluctuations in mean arterial blood pressure to assess cerebral
autoregulation. PATIENTS AND METHODS. The tissue-oxygenation index and mean arterial …