Immune checkpoint inhibitors in melanoma in the metastatic, neoadjuvant, and adjuvant setting

H Herrscher, C Robert - Current opinion in oncology, 2020 - journals.lww.com
H Herrscher, C Robert
Current opinion in oncology, 2020journals.lww.com
ICI-based immunotherapy radically modified melanoma management and now appear as
the most efficient treatment for patients with metastatic melanoma with characterized by long-
lasting cancer remissions, and a distinct spectrum of immune-related adverse events. Their
efficacy is now also established in the adjuvant setting and they are now actively evaluated
as neoadjuvant treatment with promising early results.
Summary
ICI-based immunotherapy radically modified melanoma management and now appear as the most efficient treatment for patients with metastatic melanoma with characterized by long-lasting cancer remissions, and a distinct spectrum of immune-related adverse events. Their efficacy is now also established in the adjuvant setting and they are now actively evaluated as neoadjuvant treatment with promising early results.
Lippincott Williams & Wilkins