Background Sleep disorders including insomnia, movements during sleep, and daytime
sleepiness are common but poorly studied in Huntington disease (HD). Objective To
evaluate the HD sleep-wake phenotype (including abnormal motor activity during sleep) in
patients with various HD stages and the length of CAG repeats. Because a mild hypocretin
deficiency has been found in the brains of some patients with HD (hereinafter referred to as
HD patients), we also tested the HD patients for narcolepsy. Design and Patients Twenty-five …