Nine lives for TH9s?
W Zou, NP Restifo - Nature medicine, 2012 - nature.com
Nature medicine, 2012•nature.com
There is currently much interest in dissecting the mechanisms of tumor immunity. A new
study shows that a subset of CD4+ T cells that produce the cytokine interleukin-9 (IL-9)
mediate inhibition of melanoma growth in mice and that analogous IL-9–producing T cells
are present in human skin (pages 1248–1253). Could such cells be manipulated to develop
new therapeutic strategies for melanoma?
study shows that a subset of CD4+ T cells that produce the cytokine interleukin-9 (IL-9)
mediate inhibition of melanoma growth in mice and that analogous IL-9–producing T cells
are present in human skin (pages 1248–1253). Could such cells be manipulated to develop
new therapeutic strategies for melanoma?
There is currently much interest in dissecting the mechanisms of tumor immunity. A new study shows that a subset of CD4+ T cells that produce the cytokine interleukin-9 (IL-9) mediate inhibition of melanoma growth in mice and that analogous IL-9–producing T cells are present in human skin (pages 1248–1253). Could such cells be manipulated to develop new therapeutic strategies for melanoma?
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