Large-scale molecular and tissue microarray analysis of mesothelin expression in common human carcinomas
HF Frierson Jr, CA Moskaluk, SM Powell, H Zhang… - Human pathology, 2003 - Elsevier
The 40-kilodalton processed glycoprotein, mesothelin, is highly expressed in epithelial
mesotheliomas and adenocarcinomas of the ovary (serous papillary) and pancreas, but its
expression in a large series of other common carcinomas has not been completely explored.
In the present study, we used oligonucleotide and tissue microarrays to profile the
expression of the mesothelin gene (MSLN) and encoded protein, respectively. Among 150
carcinomas of multiple anatomic sites, we found the highest average expression of MSLN in …
mesotheliomas and adenocarcinomas of the ovary (serous papillary) and pancreas, but its
expression in a large series of other common carcinomas has not been completely explored.
In the present study, we used oligonucleotide and tissue microarrays to profile the
expression of the mesothelin gene (MSLN) and encoded protein, respectively. Among 150
carcinomas of multiple anatomic sites, we found the highest average expression of MSLN in …