Manufacturing and stability of copper-histidine solution for treatment of Menkes' Kinky Hair Syndrome
T Hoppe-Tichy, TH Nguyen, BW Hentze, M Lorke - Die Pharmazie, 2005 - europepmc.org
T Hoppe-Tichy, TH Nguyen, BW Hentze, M Lorke
Die Pharmazie, 2005•europepmc.orgMenkes' Kinky Hair Syndrom is a rare, X-linked recessive multisystemic lethal disorder of
copper metabolism. Male infants who are affected usually die at the age of 2-3 years. If the
disease is diagnosed early, patients profit from subcutaneously administered copper salts.
We describe the preparation and stability of a copper-histidin solution. This solution has
some advantages in terms of stability over the solutions described in earlier publications.
This is a great advantage for the patients and their parents, because an ambulatory care or a …
copper metabolism. Male infants who are affected usually die at the age of 2-3 years. If the
disease is diagnosed early, patients profit from subcutaneously administered copper salts.
We describe the preparation and stability of a copper-histidin solution. This solution has
some advantages in terms of stability over the solutions described in earlier publications.
This is a great advantage for the patients and their parents, because an ambulatory care or a …
Menkes' Kinky Hair Syndrom is a rare, X-linked recessive multisystemic lethal disorder of copper metabolism. Male infants who are affected usually die at the age of 2-3 years. If the disease is diagnosed early, patients profit from subcutaneously administered copper salts. We describe the preparation and stability of a copper-histidin solution. This solution has some advantages in terms of stability over the solutions described in earlier publications. This is a great advantage for the patients and their parents, because an ambulatory care or a home care of this patients is possible now.
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