Impact of serum amyloid A on cellular cholesterol efflux to serum in type 2 diabetes mellitus
JGS Tsun, SWM Shiu, Y Wong, S Yung, TM Chan… - Atherosclerosis, 2013 - Elsevier
Abstract Objective Serum amyloid A (SAA) is an acute phase response protein and has
apolipoprotein properties. Since type 2 diabetes is associated with chronic subclinical
inflammation, the objective of this study is to investigate the changes in SAA level in type 2
diabetic patients and to evaluate the relationship between SAA and the capacity of serum to
induce cellular cholesterol efflux via the two known cholesterol transporters, scavenger
receptor class B type I (SR-BI) and ATP-binding cassette transporter G1 (ABCG1). Methods …
apolipoprotein properties. Since type 2 diabetes is associated with chronic subclinical
inflammation, the objective of this study is to investigate the changes in SAA level in type 2
diabetic patients and to evaluate the relationship between SAA and the capacity of serum to
induce cellular cholesterol efflux via the two known cholesterol transporters, scavenger
receptor class B type I (SR-BI) and ATP-binding cassette transporter G1 (ABCG1). Methods …