A severe case of intracranial hemorrhage due to alloimmune thrombocytopenia

F Cota, AA Zuppa, R Luciano, F Gallini… - The Journal of …, 2008 - Taylor & Francis
F Cota, AA Zuppa, R Luciano, F Gallini, I Savarese, G Alighieri, C Orchi, C Romagnoli
The Journal of Maternal-Fetal & Neonatal Medicine, 2008Taylor & Francis
Alloimmune thrombocytopenia (AIT) is an important cause of intrauterine hemorrhagic
lesions that result from platelet-antigen incompatibility between mother and foetus. Foetal
platelets are destroyed by cross-reactive maternal antibodies that cross the placenta. The
most serious complication of AIT is foetal intracranial bleeding that may eventually result in
intrauterine death or severe neurological impairments.
Alloimmune thrombocytopenia (AIT) is an important cause of intrauterine hemorrhagic lesions that result from platelet-antigen incompatibility between mother and foetus. Foetal platelets are destroyed by cross-reactive maternal antibodies that cross the placenta. The most serious complication of AIT is foetal intracranial bleeding that may eventually result in intrauterine death or severe neurological impairments.
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