Despite significant technological and conceptual advances over the last century, evaluation
of the efficacy of anti-malarial vaccines or drugs continues to rely principally on direct
microscopic visualisation of parasites on thick and/or thin Giemsa-stained blood smears.
This requires technical expertise of the microscopist, is highly subjective and error-prone,
and does not account for aberrations such as anaemia. Many published methods have
shown that flow cytometric analysis of blood is a highly versatile method that can readily …