Characterization of a new myeloid leukemia cell line with normal cytogenetics (CG-SH)

R Munker, ML Nordberg, D Veillon, BJ Williams… - Leukemia research, 2009 - Elsevier
A new myeloid leukemia cell line (CG-SH) with normal cytogenetics was established from a
patient with acute myelogenous leukemia (AML) following myelodysplastic syndrome
(MDS). The cells of CG-SH are immature blasts and have an immature myeloid phenotype
(positive for myeloperoxidase, CD7, CD34, CD38, CD117, HLA-DR, negative for CD10,
CD19, CD20, CD41, CD42). A partial expression of CD13, CD15, CD65 and a weak
expression of CD33 and CD133 was noted. The cells are negative for EBER. By molecular …