Citron-N (citron) binds activated Rho and concentrates at excitatory postsynaptic densities
on the smooth dendritic shafts of hippocampal GABAergic neurons. Since little is known
about how cytoplasmic proteins become targeted and retained at synapses, we asked how
citron attains this discrete distribution. We first sought to determine whether the synaptic
localization machinery is unique to GABAergic interneurons, but in neurons cultured from
either cerebral cortex or hippocampus, low levels of citron are found in a small population of …