[HTML][HTML] Citron rho-interacting kinase, a novel tissue-specific ser/thr kinase encompassing the Rho-Rac-binding protein Citron
F Di Cunto, E Calautti, J Hsiao, L Ong, G Topley… - Journal of Biological …, 1998 - ASBMB
We have identified a novel serine/threonine kinase belonging to the myotonic dystrophy
kinase family. The kinase can be produced in at least two different isoforms: a∼ 240-kDa
protein (Citron Rho-interacting kinase, CRIK), in which the kinase domain is followed by the
sequence of Citron, a previously identified Rho/Rac binding protein; a∼ 54-kDa protein
(CRIK-short kinase (SK)), which consists mostly of the kinase domain. CRIK and CRIK-SK
proteins are capable of phosphorylating exogenous substrates as well as of …
kinase family. The kinase can be produced in at least two different isoforms: a∼ 240-kDa
protein (Citron Rho-interacting kinase, CRIK), in which the kinase domain is followed by the
sequence of Citron, a previously identified Rho/Rac binding protein; a∼ 54-kDa protein
(CRIK-short kinase (SK)), which consists mostly of the kinase domain. CRIK and CRIK-SK
proteins are capable of phosphorylating exogenous substrates as well as of …
