The epoxide hydrolases (EHs) are enzymes present in all living organisms, which transform
epoxide containing lipids by the addition of water. In plants and animals, many of these lipid
substrates have potent biologically activities, such as host defenses, control of development,
regulation of inflammation and blood pressure. Thus the EHs have important and diverse
biological roles with profound effects on the physiological state of the host organisms.
Currently, seven distinct epoxide hydrolase sub-types are recognized in higher organisms …