Regulation of T cell migration during viral infection: role of adhesion molecules and chemokines
AR Thomsen, A Nansen, AN Madsen, C Bartholdy… - Immunology letters, 2003 - Elsevier
T cell mediated immunity and in particular CD8+ T cells are pivotal for the control of most
viral infections. T cells exclusively exert their antiviral effect through close cellular interaction
with relevant virus-infected target cells in vivo. It is therefore imperative that efficient
mechanisms exist, which will rapidly direct newly generated effector T cells to sites of viral
replication. In the present report we have reviewed our present knowledge concerning the
molecular interactions, which are important in targeting of effector CD8+ T cells to sites of …
viral infections. T cells exclusively exert their antiviral effect through close cellular interaction
with relevant virus-infected target cells in vivo. It is therefore imperative that efficient
mechanisms exist, which will rapidly direct newly generated effector T cells to sites of viral
replication. In the present report we have reviewed our present knowledge concerning the
molecular interactions, which are important in targeting of effector CD8+ T cells to sites of …
