Association of diabetes and hepatitis C infection: epidemiologic evidence and pathophysiologic insights

G Bahtiyar, JJ Shin, A Aytaman, JR Sowers… - Current diabetes …, 2004 - Springer
G Bahtiyar, JJ Shin, A Aytaman, JR Sowers, SI McFarlane
Current diabetes reports, 2004Springer
Up to one third of patients with chronic hepatitis C virus (HCV) develop type 2 diabetes
mellitus (DM). This prevalence is much higher than that observed in the general population,
and in patients with other chronic liver diseases such as hepatitis B virus, alcoholic liver
disease, and primary biliary cirrhosis. Further, HCV seropositivity in patients with DM
appears to be higher than in the general population. Postliver transplantation DM also
appears to be higher among patients with HCV. In this article, we review the epidemiologic …
Abstract
Up to one third of patients with chronic hepatitis C virus (HCV) develop type 2 diabetes mellitus (DM). This prevalence is much higher than that observed in the general population, and in patients with other chronic liver diseases such as hepatitis B virus, alcoholic liver disease, and primary biliary cirrhosis. Further, HCV seropositivity in patients with DM appears to be higher than in the general population. Postliver transplantation DM also appears to be higher among patients with HCV. In this article, we review the epidemiologic association between HCV and DM, highlighting the most recent pathophysiologic insights into the mechanisms underlying this association.
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