[HTML][HTML] Viral evasion of natural killer cells
JS Orange, MS Fassett, LA Koopman, JE Boyson… - Nature …, 2002 - nature.com
JS Orange, MS Fassett, LA Koopman, JE Boyson, JL Strominger
Nature immunology, 2002•nature.comViruses have evolved mechanisms to avoid the host immune system, including means of
escaping detection by both the innate and adaptive immune responses. Natural killer (NK)
cells are a central component of the innate immune system and are crucial in defense
against certain viruses. To attain a state of chronic infection, some successful viruses have
developed specific mechanisms to evade detection by and activation of NK cells. These NK
cell–specific evasion mechanisms fall into distinct mechanistic categories used in numerous …
escaping detection by both the innate and adaptive immune responses. Natural killer (NK)
cells are a central component of the innate immune system and are crucial in defense
against certain viruses. To attain a state of chronic infection, some successful viruses have
developed specific mechanisms to evade detection by and activation of NK cells. These NK
cell–specific evasion mechanisms fall into distinct mechanistic categories used in numerous …
Abstract
Viruses have evolved mechanisms to avoid the host immune system, including means of escaping detection by both the innate and adaptive immune responses. Natural killer (NK) cells are a central component of the innate immune system and are crucial in defense against certain viruses. To attain a state of chronic infection, some successful viruses have developed specific mechanisms to evade detection by and activation of NK cells. These NK cell–specific evasion mechanisms fall into distinct mechanistic categories used in numerous virus families.
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