Clinical and laboratory observations in cases of triiodothyronine toxicosis confirmed by radioimmunoassay

CS Hollander, T Mitsuma, N Nihei, L Shenkman… - The Lancet, 1972 - Elsevier
CS Hollander, T Mitsuma, N Nihei, L Shenkman, SZ Burday, M Blum
The Lancet, 1972Elsevier
Forty patients with triiodothyronine (T3) toxicosis have been identified. All were clinically
hyperthyroid with raised levels of both total and free T3 but normal serum concentrations of
total and free thyroxine and normal thyroxine-binding globulin capacities. Twenty-nine
presented as Graves' disease, eight as autonomous adenoma, and three as toxic
multinodular goitre. The availability of the radioimmunoassay for T3 should permit more
frequent recognition of this disorder.
Abstract
Forty patients with triiodothyronine (T3) toxicosis have been identified. All were clinically hyperthyroid with raised levels of both total and free T3 but normal serum concentrations of total and free thyroxine and normal thyroxine-binding globulin capacities. Twenty-nine presented as Graves' disease, eight as autonomous adenoma, and three as toxic multinodular goitre. The availability of the radioimmunoassay for T3 should permit more frequent recognition of this disorder.
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