Heat shock protein-peptide complexes in cancer immunotherapy
PK Srivastava, H Udono - Current opinion in immunology, 1994 - Elsevier
PK Srivastava, H Udono
Current opinion in immunology, 1994•ElsevierHeat shock proteins (HSPs) are associated with a broad spectrum of peptides derived from
the cells from which they are isolated. Vaccination with such HSP-peptide complexes elicits
protective immunity against tumors or other cells used as the source of HSPs. These
observations suggest that HSP-peptide complexes are suitable as vaccines against cancers
and infectious diseases.
the cells from which they are isolated. Vaccination with such HSP-peptide complexes elicits
protective immunity against tumors or other cells used as the source of HSPs. These
observations suggest that HSP-peptide complexes are suitable as vaccines against cancers
and infectious diseases.
Abstract
Heat shock proteins (HSPs) are associated with a broad spectrum of peptides derived from the cells from which they are isolated. Vaccination with such HSP-peptide complexes elicits protective immunity against tumors or other cells used as the source of HSPs. These observations suggest that HSP-peptide complexes are suitable as vaccines against cancers and infectious diseases.
Elsevier