[PDF][PDF] Changes in brain glucose metabolism in cocaine dependence and withdrawal.
ND Volkow, JS Fowler, AP Wolf… - American Journal of …, 1991 - researchgate.net
The authors investigated changes in brain function associated with cocaine dependence
and withdrawal to provide clues regarding the processes that lead to the uncontrollable self—
administration of cocaine. Method: They measured regional brain metabolism with [ISFj-
fluorodeoxyglucose (FDG) and positron emission tomography in 15 outpatients with the
diagnosis of cocaine abuse and 17 normal comparison subjects. Ten of the patients were
studied less than 1 week after they had last had cocaine, and five were studied 2—4 weeks …
and withdrawal to provide clues regarding the processes that lead to the uncontrollable self—
administration of cocaine. Method: They measured regional brain metabolism with [ISFj-
fluorodeoxyglucose (FDG) and positron emission tomography in 15 outpatients with the
diagnosis of cocaine abuse and 17 normal comparison subjects. Ten of the patients were
studied less than 1 week after they had last had cocaine, and five were studied 2—4 weeks …