Strong association of HLA class II sequences in Mexicans with Vogt-Koyanagi-Harada's disease
C Alaez, M del Pilar Mora, L Arellanes, S Cano… - Human immunology, 1999 - Elsevier
Vogt-Koyanagi-Harada's syndrome (VKH) is an autoimmune disease prevalent in
Mongoloids with evident participation of HLA. The aim of this study was to identify the class II
DNA sequences involved in the etiopathogenesis of VKH in Mexican Mestizos. This study
included 46 VKH patients and 170 controls. 75% were females (mean age at onset of 33.5
years). The disease evolved to chronicity (68%) and 25% of the patients were unresponsive
to corticotherapy. DNA typing of HLA-DRB1, DQA1 and DQB1 was done following the 12th …
Mongoloids with evident participation of HLA. The aim of this study was to identify the class II
DNA sequences involved in the etiopathogenesis of VKH in Mexican Mestizos. This study
included 46 VKH patients and 170 controls. 75% were females (mean age at onset of 33.5
years). The disease evolved to chronicity (68%) and 25% of the patients were unresponsive
to corticotherapy. DNA typing of HLA-DRB1, DQA1 and DQB1 was done following the 12th …
